The only true full stack, cell free DNA platform.

NunaBio synthesises its own oligos, assembles them into complex constructs, and amplifies DNA with a purely enzymatic, cell free process. One partner from design to delivered DNA means fewer handoffs and faster iteration.

Speed that compresses your design, build, test cycle.

Our end-to-end cell free workflow moves from sequence to material in days, not weeks. No waiting on cell growth or plasmid prep shortens critical paths. Parallelized synthesis and amplification unlock high throughput without bottlenecks, keeping your teams on track.

Complexity without compromise.

We handle long inserts, repeat rich regions, GC extremes, and challenging structural motifs. Assembly is a solved problem inside NunaBio, so complexity does not add friction. You design for biology, not for the limitations of a manufacturing method.

Exceptional fidelity and purity.

Our enzymatic process delivers a 1 in 100000 error or mismatch rate, backed by rigorous QC. Cell free manufacturing avoids endotoxin, antibiotics, and host derived contaminants. You receive sequence verified DNA with the quality to go straight into critical experiments with clearer data and fewer repeats.

Scale that grows with your program.

Order micrograms for early screening, milligrams for process work, and scale beyond as you move toward manufacturing. Lead time remains stable as you scale because there are no cell based steps to saturate. Your project never outgrows the platform.

Scale sustainably while remaining flexible.

Cell free and enzymatic means lower water and energy use reduces footprint and cost sensitivity. Less plastic and media waste supports your ESG goals without trade offs in performance.

Minicircles that power expression, processability, and safety.

Minicircle DNA removes bacterial backbone sequences, which reduces immunogenic motifs and can improve transfection efficiency. Higher specific expression per microgram supports transient mAb production and accelerates clone screening. Clean, backbone free templates improve in vitro transcription for mRNA manufacturing with less process noise. In cell and gene therapy, minicircles support non viral delivery, HDR donor templates, and stable expression studies with fewer regulatory red flags.

Modified DNA for advanced functionality.

NunaBio can incorporate commercially available modified dNTPs during synthesis, enabling chemical handles such as azide groups. These reactive sites allow you to attach fluorophores, linkers, or conjugates for downstream applications. This flexibility supports click chemistry, targeted delivery systems, and functionalized constructs for diagnostics or therapeutics. You get custom chemistry without compromising speed or quality.