Our technology can be used to make high concentrations of closed-ended DNA/genes (non-plasmid). The surface confined reaction means purification is straightforward and cost effective, processing time is vastly reduced compared to other methods and a multi-array format approach to conventional gene synthesis is now possible. Key applications include non-viral gene synthesis and delivery, viral vector synthesis and gene/fragment synthesis.
Applying our technology to biosensing, the readout is amplified compared to conventional methods. Our platforms are cheaper, portable and provide accurate detection of the target DNA with reduced cost of components, signal processing requirements and power consumption. We can detect a small number of base discrepancies in a DNA sequence and our technology can be applied to a number of sensing platforms including electrochemical, optical and chemiluminescence.
Our ability to anchor ssDNA capture probes to solid surfaces provides a number of near-term opportunities in areas with high need. By anchoring our technology to micro-arrays, well-plates and other solid substrates we are able to offer a range of high-value research and clinical tools. Applications include next generation sequencing, biomarker panels, SNP genotyping and gene expression kits. We can also use this approach to improve the performance of existing biosensor platforms by providing enhanced signal output for products already on market.